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1.她把我的秘密告诉所有的人，真让人忍无可忍。She told my secret to evryone.That is the last straw.
2.真让人忍无可忍，她不再是我的朋友。That's the last straw.She is not my friends any more.
3.又下雨了，真让人忍无可忍。It is rainning, that is the last atraw.